Esnats Publications 2009 - 2010

• Poet Torka S, Kirman Chris R, Bader Michael, van Thriel, Christoph, Gargas, Michael L, Hinderliter Paul M, "Quantitative Risk Analysis for N-Methyl Pyrrolidone Using Physiologically Based Pharmacokinetic and Benchmark Dose Modeling", Toxicological Sciences, February 2010.
• Colleoni S, Galli C, Giannelli SG, Armentero MT, Blandini F, Broccoli V, Lazzari G, "Long-term culture and differentiation of CNS precursors derived from anterior human neural rosettes following exposure to ventralizing factors", Experimental Cell Research, February 2010.
• Kuegler PB, Zimmer B, Waldmann T, Baudis B, Ilmjärv S, Hescheler J, Gaughwin P, Brundin P, Mundy W, Bal-Price AK, Schrattenholz A, Krause KH, van Thriel C, Rao MS, Kadereit S, Leist M, "Markers of Murine Embryonic and Neural Stem Cells, Neurons and Astrocytes: Reference Points for Developmental Neurotoxicity Testing", Altex, January 2010.
• Godoy P, Lakkapamu S, Schug M, Bauer A, Stewart JD, Bedawi E, Hammad S, Amin J, Marchan R, Schormann W, Maccoux L, von Recklinghausen I, Reif R, Hengstler JG, "Dexamethasone-dependent versus -independent markers of epithelial to mesenchymal transition in primary hepatocytes", Biological Chemistry, January 2010.
• Bolt HM, Hengstler JG, "Oxidative stress and hepatic carcinogenesis: new insights and applications", Archives of Toxicology, January 2010.
• Vanhaecke T, Snykers S, Rogiers V, Garthoff B, Castell JV, Hengstler JG, "EU research activities in alternative testing strategies: current status and future perspectives", Archives of Toxicology, December 2009.
• De Kock J, Vanhaecke T, Biernaskie J., Rogiers V. and Snykers S, "Characterization and hepatic differentiation of skin-derived precursors from adult foreskin by sequential exposure to hepatogenic cytokines and growth factors reflecting liver development", Toxicology in Vitro, December 2009.
• Schober C, Schiller J, Pinker F, Hengstler JG, Fuchs B, "Lysophosphatidylethanolamine is - in contrast to - choline - generated under in vivo conditions exclusively by phospholipase A2 but not by hypochlorous acid", Bioorganic Chemistry, December 2009.
• Schildknecht S, Pöltl D, Nagel DM, Matt F, Scholz D, Lotharius J, Schmieg N, Salvo-Vargas A, Leist M, "Requirement of a dopaminergic neuronal phenotype for toxicity of low concentrations of 1-methyl-4-phenylpyridinium to human cells, Toxicology and Applied Pharmacology", Toxicology & Applied Pharmacology, November 2009.
• Franke H, Sauer C, Rudolph C, Krügel U, Hengstler JG, Illes P, "P2 receptor-mediated stimulation of the PI3-K/Akt-pathway in vivo", Glia, August 2009.
• Snykers S, Henkens T, De Rop E, Vinken M, Fraczek J, De Kock J, De Prins E, Geerts A, Rogiers V, Vanhaecke T, "Role of epigenetics in liver-specific gene transcription, hepatocyte differentiation, and stem cell reprogrammation", Journal of Hepatology, EASL, July 2009.
• Weng HL, Liu Y, Chen JL, Huang T, Xu LJ, Godoy P, Hu JH, Zhou C, Stickel F, Marx A, Bohle RM, Zimmer V, Lammert F, Mueller S, Gigou M, Samuel D, Mertens PR, Singer MV, Seitz HK, Dooley S, "The etiology of liver damage imparts cytokines transforming growth factor beta1 or nterleukin-13 as driving forces in fibrogenesis", Hepatology, July 2009.
• Colleoni S, "Generation of dopaminergic neurons proliferating precursors from human embryonic stem cells", ISSCR Proceedings of 7th ISSCR Annual Meeting July 2009.
• Godoy P, Hengstler JG, Ilkavets I, Meyer C, Bachmann A, Müller A, Tuschl G, Mueller SO, Dooley S, "Extracellular matrix modulates sensitivity of hepatocytes to fibroblastoid dedifferentiation and transforming growth factor beta-induced apoptosis", Hepatology, June 2009.
• Ullrich A, Stolz DB, Ellis EC, Strom SC, Michalopoulos GK, Hengstler JG, Runge D, "Long term cultures of primary human hepatocytes as an alternative to drug testing in animals", Altex, April 2009.
• Riquelme P, Wundt J, Hutchinson JA, Brulport M, Jun Y, Sotnikova A, Girreser U, Braun F, Gövert F, Soria B, Nüssler A, Clement B, Hengstler JG, Fändrich F, "A refined characterisation of the NeoHepatocyte phenotype necessitates a reappraisal of the transdifferentiation hypothesis", Differentiation, Research in Biological Diversity, March 2009.
• Henn A, Lund S, Hedtjärn M, Schrattenholz A, Pörzgen P, Leist M, "The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation", Altex, 2009.
• Winkler J, Sotiriadou I, Chen S, Hescheler J, Sachinidis A, "The potential of embryonic stem cells combined with -omics technologies as model systems for toxicology", Current Medicinal Chemistry, 2009.
• Hengstler JG, "OMICS-Techniken in der Toxikologie: Möglichkeiten und Grenzen", Österreichisches Forum Arbeitsmedizin, 2009.
• Snykers S, De Kock J, Rogiers V, Vanhaecke T, "In vitro differentiation of embryonic and adult stem cells into hepatocytes: state of the art", Stem Cells, December 2008.
• H Aurich, M Sgodda, P Kaltwaßer, M Vetter, A Weise, T Liehr, M Brulport, J G Hengstler, M M Dollinger, W E Fleig, B Christ , "Hepatocyte differentiation of mesenchymal stem cells from human adipose tissue in vitro promotes hepatic integration in vivo", GUT, November 2008.